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Article

Turning it on and off: M-phase promoting factor during meiotic maturation and fertilization

9 Dec 2003

Abstract excerpt

Maturation (M-phase) promoting factor (MPF) plays a pivotal role in oocytes during their maturation. This review concentrates on its function at three important time-points. First, its activation during meiotic progression from prophase I arrest at germinal vesicle breakdown. Second, its role during the transition from meiosis I to meiosis II, a defining feature of meiosis involving segregation of homologous...

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PMID: 14665700
DOI: 10.1093/molehr/gah009

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