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Article

The art of oocyte meiotic arrest regulation

5 Jan 2019

Abstract excerpt

A central dogma of mammalian reproductive biology is that the size of the primordial follicle pool represents reproductive capacity in females. The assembly of the primordial follicle starts after the primordial germ cells (PGCs)-derived oocyte releases from the synchronously dividing germline cysts. PGCs initiate meiosis during fetal development. However, after synapsis and recombination of homologous...

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PMID: 30611263
DOI: 10.1186/s12958-018-0445-8

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