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Telomere shortening and DNA damage in culprit cells of different types of progressive fibrosing interstitial lung disease

14 Jan 2021

Abstract excerpt

Pulmonary fibrosis is strongly associated with telomere shortening and increased DNA damage. Key cells in the pathogenesis involve alveolar type 2 (AT2) cells, club cells and myofibroblasts; however, to what extent these cells are affected by telomere shortening and DNA damage is not yet known. We sought to determine the degree of, and correlation between, telomere shortening and DNA damage in different cell...

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Share to Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34084786
DOI: 10.1183/23120541.00691-2020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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