Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Kinetoplastid kinetochore proteins KKT2 and KKT3 have unique centromere localization domains.

The Journal of cell biology - 2 Aug 2021

Marcianò Gabriele, Ishii Midori, Nerusheva Olga O, Akiyoshi Bungo

Abstract excerpt

The kinetochore is the macromolecular protein complex that assembles onto centromeric DNA and binds spindle microtubules. Evolutionarily divergent kinetoplastids have an unconventional set of kinetochore proteins. It remains unknown how kinetochores assemble at centromeres in these organisms. Here, we characterize KKT2 and KKT3 in the kinetoplastid parasite Trypanosoma brucei. In addition to the N-terminal kinase...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Kinetochores
Share to Models, Molecular
Share to Protein Binding

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Protein Interaction Domains and Motifs

Share to Protozoan Proteins

Share to Structure-Activity Relationship

Share to Trypanosoma brucei brucei

Source

Open in PubMed Open full text

Identifiers

PMID: 34081090
DOI: 10.1083/jcb.202101022
PMCID: PMC8178753

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Kinetoplastid kinetochore proteins KKT2 and KKT3 have unique centromere localization domains.PMID 34081090Read ↗

A CLK1-KKT2 Signaling Pathway Regulating Kinetochore Assembly in Trypanosoma bruceiSemantic proximity Read ↗

Dynamic localization of the chromosomal passenger complex in trypanosomes is controlled by the orphan kinesins KIN-A and KIN-BSemantic proximity Read ↗

Trypanosome outer kinetochore proteins suggest conservation of chromosome segregation machinery across eukaryotesSemantic proximity Read ↗

First Genome-Wide Centromere Map of <i>Trypanosoma cruzi</i> Reveals Linear and 3D Compartment Boundaries and Spatial ClusteringSemantic proximity Read ↗

Chl4p and iml3p are two new members of the budding yeast outer kinetochore.Semantic proximity Read ↗

Polo kinase recruitment via the constitutive centromere-associated network at the kinetochore elevates centromeric RNA.Semantic proximity Read ↗

Ndc10 is a platform for inner kinetochore assembly in budding yeast.Semantic proximity Read ↗

Synthetic physical interactions map kinetochore regulators and regions sensitive to constitutive Cdc14 localization.Semantic proximity Read ↗

CENP-T-W-S-X forms a unique centromeric chromatin structure with a histone-like fold.Semantic proximity Read ↗

Insights into human outer kinetochore assembly and force transmission from a structure-function analysis of the KMN networkSemantic proximity Read ↗

The pseudo GTPase CENP-M drives human kinetochore assembly.Semantic proximity Read ↗

Roles for the conserved spc105p/kre28p complex in kinetochore-microtubule binding and the spindle assembly checkpoint.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.