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Article

Histologic and genomic features of breast cancers with alterations affecting the SWI/SNF (SMARC) genes.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Oct 2021

Schwartz Christopher J, Pareja Fresia, da Silva Edaise M, Selenica Pier, Ross Dara S, Weigelt Britta, Brogi Edi, Reis-Filho Jorge S, Wen Hannah Y

Abstract excerpt

The SWI/SNF family of proteins is a multisubunit ATPase complex frequently altered in human cancer. Inactivating mutations in SWI/SNF-related matrix-associated actin-dependent regulator of chromatin (SMARCs) underpin a subset of tumors such as the malignant rhabdoid tumor and small cell carcinoma of the ovary, hypercalcemic type. Here, we investigated the genotypic and phenotypic characteristics of breast cancers...

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Identifiers

PMID: 34079072
DOI: 10.1038/s41379-021-00837-3
PMCID: PMC8448940

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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