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Article

The Role of Serotonin in Breast Cancer Stem Cells.

Molecules (Basel, Switzerland) - 26 May 2021

Gwynne William D, Shakeel Mirza S, Girgis-Gabardo Adele, Hassell John A

Abstract excerpt

Breast tumors were the first tumors of epithelial origin shown to follow the cancer stem cell model. The model proposes that cancer stem cells are uniquely endowed with tumorigenic capacity and that their aberrant differentiation yields non-tumorigenic progeny, which constitute the bulk of the tumor cell population. Breast cancer stem cells resist therapies and seed metastases; thus, they account for breast...

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Identifiers

PMID: 34073226
DOI: 10.3390/molecules26113171
PMCID: PMC8198186

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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