Alternative Viewpoint Against Breast Cancer Based on Selective Serotonin Receptors 5HTR3A and 5HTR2A Antagonists that can Mediate Apoptosis in MCF-7 Cell Line

Abstract excerpt

BACKGROUND: Neurotransmitters had progressive effects on various cancers via their different type of receptors. OBJECTIVE: This study was conducted to determine the pattern of serotonin receptors, respectively, 5HTR2A and 5HTR3A gene expression in MCF-7 cells and evaluate their selective antagonist effects on them. METHOD: RT-PCR was performed to determine the pattern of serotonin receptor gene expression in...

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