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Genistein decreases the breast cancer stem-like cell population through Hedgehog pathway

11 Dec 2013

Abstract excerpt

INTRODUCTION: The existence of breast cancer stem-like cells (BCSCs) has profound implications for cancer prevention. Genistein, a predominant isoflavone found in soy products, has multiple robust anti-tumor effects in various cancers, especially in the breast and prostate cancer. In this study, we aimed to evaluate genistein inhibition of BCSCs and its potential mechanism by culturing MCF-7 breast cancer cells...

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PMID: 24331293
DOI: 10.1186/scrt357

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