Article
Bruton's tyrosine kinase: potential target in human multiple myeloma.
Leukemia & lymphoma - 1 Jan 2014
Liu Ying, Dong Ying, Jiang Qian-Li, Zhang Bo, Hu An-Mei
Abstract excerpt
Bruton's tyrosine kinase (BTK), a Tec family non-receptor tyrosine kinase that is required for B cell development, is critical for the initiation and maintenance of human B-cell malignancies. However, the expression of BTK and the role that BTK plays in the pathogenesis of multiple myeloma (MM) remain seldom reported. In this study we examined the expression and screened for gene mutations of BTK in MM cells. We...
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