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Article

Effect of Sodium Valproate on the Conformational Stability of the Visual G Protein-Coupled Receptor Rhodopsin.

Molecules (Basel, Switzerland) - 19 May 2021

Razzaghi Neda, Fernandez-Gonzalez Pol, Mas-Sanchez Aina, Vila-Julià Guillem, Perez Juan Jesus, Garriga Pere

Abstract excerpt

Rhodopsin is the G protein-coupled receptor of rod photoreceptor cells that mediates vertebrate vision at low light intensities. Mutations in rhodopsin cause inherited retinal degenerative diseases such as retinitis pigmentosa. Several therapeutic strategies have attempted to address and counteract the deleterious effect of rhodopsin mutations on the conformation and function of this photoreceptor protein, but...

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Identifiers

PMID: 34069614
DOI: 10.3390/molecules26103032
PMCID: PMC8160834

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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