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Article

Misfolded rhodopsin mutants display variable aggregation properties.

Biochimica et biophysica acta. Molecular basis of disease - 1 Sept 2018

Gragg Megan, Park Paul S-H

Abstract excerpt

The largest class of rhodopsin mutations causing autosomal dominant retinitis pigmentosa (adRP) is mutations that lead to misfolding and aggregation of the receptor. The misfolding mutants have been characterized biochemically, and categorized as either partial or complete misfolding mutants. This classification is incomplete and does not provide sufficient information to fully understand the disease pathogenesis...

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Identifiers

PMID: 29890221
DOI: 10.1016/j.bbadis.2018.06.004
PMCID: PMC6066411

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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