Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Cellular Composition of Bovine Coccygeal Intervertebral Discs: A Comprehensive Single-Cell RNAseq Analysis

6 May 2021

Abstract excerpt

Intervertebral disc (IVD) degeneration and its medical consequences is still one of the leading causes of morbidity worldwide. To support potential regenerative treatments for degenerated IVDs, we sought to deconvolute the cell composition of the nucleus pulposus (NP) and the annulus fibrosus (AF) of bovine intervertebral discs. Bovine calf tails have been extensively used in intervertebral disc research as a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cervical and Thoracic Myelopathy
Share to Spine and Intervertebral Disc Pathology
Share to TGF-β signaling in diseases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34066404
DOI: 10.3390/ijms22094917

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 20 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Cellular Composition of Bovine Coccygeal Intervertebral Discs: A Comprehensive Single-Cell RNAseq AnalysisPMID 34066404Read ↗

Single-cell RNA-sequencing atlas of bovine caudal intervertebral discs: Discovery of heterogeneous cell populations with distinct roles in homeostasis.Semantic proximity Read ↗

Single-cell sequencing: New insights for intervertebral disc degenerationSemantic proximity Read ↗

Potential biomarkers of the mature intervertebral disc identified at the single cell levelSemantic proximity Read ↗

Single-cell RNA-seq identifies unique transcriptional landscapes of human nucleus pulposus and annulus fibrosus cellsSemantic proximity Read ↗

Single-cell sequencing reveals cellular heterogeneity of nucleus pulposus in intervertebral disc degenerationSemantic proximity Read ↗

Integrated proteome sequencing, bulk RNA sequencing and single-cell RNA sequencing to identify potential biomarkers in different grades of intervertebral disc degenerationSemantic proximity Read ↗

Spatially defined single-cell transcriptional profiling characterizes diverse chondrocyte subtypes and nucleus pulposus progenitors in human intervertebral discsSemantic proximity Read ↗

Transcriptomic and functional comparison of cells isolated from healthy and degenerated ovine intervertebral discsSemantic proximity Read ↗

Transcriptional profiling of bovine intervertebral disc cells: implications for identification of normal and degenerate human intervertebral disc cell phenotypes.Semantic proximity Read ↗

Single-Cell RNA-Seq Analysis of Cells from Degenerating and Non-Degenerating Intervertebral Discs from the Same Individual Reveals New Biomarkers for Intervertebral Disc DegenerationSemantic proximity Read ↗

Single-cell Atlas Unveils Cellular Heterogeneity and Novel Markers in Human Neonatal and Adult Intervertebral DiscsSemantic proximity Read ↗

Single-cell atlas unveils cellular heterogeneity and novel markers in human neonatal and adult intervertebral discsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.