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Potential biomarkers of the mature intervertebral disc identified at the single cell level

18 Nov 2018

Abstract excerpt

Intervertebral disc (IVD) degeneration and trauma is a major socio-economic burden and the focus of cell-based regenerative medicine approaches. Despite numerous ongoing clinical trials attempting to replace ailing IVD cells with mesenchymal stem cells, a solid understanding of the identity and nature of cells in a healthy mature IVD is still in need of refinement. Although anatomically simple, the IVD is...

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PMID: 30450595
DOI: 10.1111/joa.12904

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