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Article

MAT2A Localization and Its Independently Prognostic Relevance in Breast Cancer Patients

20 May 2021

Abstract excerpt

(1) Background: methionine cycle is not only essential for cancer cell proliferation but is also critical for metabolic reprogramming, a cancer hallmark. Hepatic and extrahepatic tissues methionine adenosyltransferases (MATs) are products of two genes, MAT1A and MAT2A that catalyze the formation of S-adenosylmethionine (SAM), the principal biological methyl donor. Glycine N-methyltransferase (GNMT) further...

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PMID: 34065390
DOI: 10.3390/ijms22105382

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