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Article

Differential expression of enzymes associated with serine/glycine metabolism in different breast cancer subtypes.

PloS one - 1 Jan 2014

Kim Sang Kyum, Jung Woo Hee, Koo Ja Seung

Abstract excerpt

PURPOSE: Glycine and serine are well-known, classic metabolites of glycolysis. Here, we profiled the expression of enzymes associated with serine/glycine metabolism in different molecular subtypes of breast cancer and discuss their potential clinical implications. METHODS: We used western blotting and immunohistochemistry to examine five serine-/glycine-metabolism-associated proteins (PHGDH, PSAT, PSPH, SHMT, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24979213
DOI: 10.1371/journal.pone.0101004
PMCID: PMC4076239

Genes

PSPH
GLDC
PHGDH
SHMT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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