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MAT1A activation of glycolysis to promote NSCLC progression depends on stabilizing CCND1

22 Oct 2024

Abstract excerpt

Non-small cell lung cancer (NSCLC) remains a cause for concern as the leading cause of cancer-related death worldwide. Amidst ongoing debates on the role and mechanisms of methionine adenosyltransferase 1A (MAT1A) in cancer, our study sheds light on its significance in NSCLC. Leveraging TCGA database and immunohistochemical staining, we systematically analyzed MAT1A expression in NSCLC, uncovering its marked...

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PMID: 39438468
DOI: 10.1038/s41419-024-07113-7

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