Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Oocyte aging is controlled by mitogen‐activated protein kinase signaling

1 Jun 2021

Abstract excerpt

Oogenesis is one of the first processes to fail during aging. In women, most oocytes cannot successfully complete meiotic divisions already during the fourth decade of life. Studies of the nematode Caenorhabditis elegans have uncovered conserved genetic pathways that control lifespan, but our knowledge regarding reproductive aging in worms and humans is limited. Specifically, little is known about germline...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetics, Aging, and Longevity in Model Organisms
Share to Pluripotent Stem Cells Research
Share to Reproductive Biology and Fertility

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34061407
DOI: 10.1111/acel.13386

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Oocyte aging is controlled by mitogen‐activated protein kinase signalingPMID 34061407Read ↗

Oocyte Aging is Controlled by Mitogen Activated Protein Kinase SignalingSemantic proximity Read ↗

Novel insights into reproductive ageing and menopause from genomicsSemantic proximity Read ↗

Apoptosis maintains oocyte quality in aging Caenorhabditis elegans females.Semantic proximity Read ↗

Aging and sperm signals alter DNA break formation and repair in the <i>C. elegans</i> germlineSemantic proximity Read ↗

<i>Caenorhabditis elegans</i> reproductive aging: Regulation and underlying mechanismsSemantic proximity Read ↗

Oocyte aging: looking beyond chromosome segregation errorsSemantic proximity Read ↗

Single‐oocyte transcriptome analysis reveals aging‐associated effects influenced by life stage and calorie restrictionSemantic proximity Read ↗

A decline in follicle cell function is a major driver of <i>Drosophila</i> ovarian agingSemantic proximity Read ↗

The role of declining ataxia-telangiectasia-mutated (ATM) function in oocyte agingSemantic proximity Read ↗

Control of mitochondrial integrity influences oocyte quality during reproductive agingSemantic proximity Read ↗

Oocyte mitophagy is critical for extended reproductive longevitySemantic proximity Read ↗

Ovarian aging: mechanisms and intervention strategiesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.