Article
Computational modeling of intramolecular and intermolecular communication in GPCRs.
Current protein & peptide science - 1 Apr 2009
Fanelli Francesca, De Benedetti Pier G, Raimondi Francesco, Seeber Michele
Abstract excerpt
Intramolecular and intermolecular communication is a privileged issue in G protein-Coupled Receptor (GPCR) function as the prominent role of these receptors is to respond to extracellular signals by catalyzing nucleotide exchange in intracellular G proteins. In the last decade or so we have applied much effort in elaborating computational strategies to infer the mechanisms of intramolecular and intermolecular...
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