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Towards 3D Structures of G Protein-Coupled Receptors A Multidisciplinary Approach

1 Sept 2000

Abstract excerpt

Current strategies in pharmaceutical research comprise two methodologically different but complementary approaches for lead finding purposes, namely the random screening of compound libraries and the structure-based effort, commonly termed rational drug design. The structure-based approach is aimed to exploit 3D structure data of the molecular compo-nents involved in the molecular recognition event that underlies...

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PMID: 10911020
DOI: 10.2174/0929867003374534

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