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Article

TNPO1-mediated nuclear import of ARID1B promotes tumor growth in ARID1A-deficient gynecologic cancer.

Cancer letters - 1 Sept 2021

Yang Bikang, Chen Jing, Li Xiao, Zhang Xueli, Hu Lipeng, Jiang Shuheng, Zhang Zhigang, Teng Yincheng

Abstract excerpt

Karyopherin-β proteins are critically involved in cancer progression and have been reported as potential biomarkers and therapeutic targets for tumor treatment. However, TNPO1, as an important karyopherin-β family member, underlying functional roles in cancers remain largely unclear. In this study, under integrated gene-expression profiling screen of karyopherin-β in gynecologic cancer, we identify TNPO1 as a...

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Identifiers

PMID: 34044070
DOI: 10.1016/j.canlet.2021.05.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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