Article

IRF2 Destabilizes Oncogenic KPNA2 to Modulate the Tumorigenesis of Osteosarcoma via Regulating NF-κB/p65

2021-08-02

Abstract excerpt

<h4>Background: </h4> Osteosarcomas (OS) are the most frequent primary malignant bone tumor. Emerging evidence revealed that karyopherin alpha 2 (KPNA2) was strongly associated with the tumorigenesis and development of numerous human cancers. The aim of the present study was to investigate the expression pattern, biological functions and underlying mechanism of KPNA2 in OS. <h4>Methods: </h4>: Bioinformatics TFBIN...

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Literature Corpus work: 54bbf6c3-8968-5b02-93f3-51636ba457cc
DOI: 10.21203/rs.3.rs-701134/v1

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