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Article

Triple-mutated oncolytic herpes virus for treating both fast- and slow-growing tumors.

Cancer science - 1 Aug 2021

Fukuhara Hiroshi, Takeshima Yuta, Todo Tomoki

Abstract excerpt

Oncolytic virus therapy has emerged as a promising treatment option against cancer. To date, oncolytic viruses have been developed for malignant tumors, but the need for this new therapeutic modality also exists for benign and slow-growing tumors. G47∆ is an oncolytic herpes simplex virus type 1 (HSV-1) with an enhanced replication capability highly selective to tumor cells due to genetically engineered, triple...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34036669
DOI: 10.1111/cas.14981
PMCID: PMC8353919

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