Viral oncolysis by herpes simplex virus and other viruses.

Abstract excerpt

The use of viruses to destroy tumors, also known as viral oncolysis, dates back to the early 1900's. Although the mechanism of cancer cell lysis was unknown in the early years of development, advances in tumor biology, molecular biology, and virology have been critical for numerous advances that have brought the field to where it is today. Oncolytic viruses have been developed based on innate and engineered...

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