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Article

A conserved klo-1-mpk-1 pathway regulates autophagy and modulates longevity in Caenorhabditis elegans.

Biochemical and biophysical research communications - 12 Jul 2021

Tang Jie, Zhang Jian-Fan, Yang Rui-Qiu, Chen Yuan-Li, Ni Baosen

Abstract excerpt

There are six different longevity models in Caenorhabditis elegans. Previous studies have identified several convergence points, such as hlh-30, daf-16, and klf-3, required for lifespan extension in these longevity models. However, it is not clear whether there other such convergence points. In this study, based on analysis of transcriptome data, we found that the expression of klo-1/klotho was elevated in...

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PMID: 34034091
DOI: 10.1016/j.bbrc.2021.05.042

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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