Article
Large-Scale Identification of Clonal Hematopoiesis and Mutations Recurrent in Blood Cancers.
Blood cancer discovery - 1 May 2021
Feusier Julie E, Arunachalam Sasi, Tashi Tsewang, Baker Monika J, VanSant-Webb Chad, Ferdig Amber, Welm Bryan E, Rodriguez-Flores Juan L, Ours Christopher, Jorde Lynn B, Prchal Josef T, Mason Clinton C
Abstract excerpt
Clonal hematopoiesis of indeterminate potential (CHIP) is characterized by detectable hematopoietic-associated gene mutations in a person without evidence of hematologic malignancy. We sought to identify additional cancer-presenting mutations useable for CHIP detection by performing a data mining analysis of 48 somatic mutation studies reporting mutations at diagnoses of 7,430 adult and pediatric patients with...
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