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Article

SOX9 has distinct roles in the formation and progression of different non‐small cell lung cancer histotypes

22 May 2021

Abstract excerpt

Abstract The transcription factor SOX9 is a key regulator of multiple developmental processes and is frequently re‐expressed in non‐small cell lung cancer (NSCLC). Its precise role in the progression of NSCLC histotypes has, however, remained elusive. We show that SOX9 expression relates to poor overall survival and invasive histopathology in human non‐mucinous adenocarcinoma and is absent in murine early...

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PMID: 34021911
DOI: 10.1002/path.5733

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