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Article

The role of SOX2 in small cell lung cancer, lung adenocarcinoma and squamous cell carcinoma of the lung.

1 Jun 2013

Abstract excerpt

SOX2 is a stem cell transcription factor that plays a crucial role in the regulation of embryonic development. It is one of the genes in a set of factors (Oct4, SOX2, Nanog) that are able to reprogram human somatic cells to pluripotent stem cells. Overexpression of SOX2 has been described in all types of lung cancer tissues, including small cell and squamous cell carcinoma but also adenocarcinoma. An in-depth...

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Identifiers

PMID: 25806230
DOI: 10.3978/j.issn.2218-6751.2013.01.01

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