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Article

RAGE-mediated functional DNA methylated modification contributes to cigarette smoke-induced airway inflammation in mice

21 May 2021

Abstract excerpt

Our previous study indicated knockout of receptor for advanced glycation end-products (RAGE) significantly attenuated cigarette smoke (CS)-induced airway inflammation in mice. In the present study, we aim to further detect the mediatory effects of RAGE in DNA methylated modification in CS-induced airway inflammation. Lung tissues from the CS-exposed mouse model of airway inflammation were collected for profiling...

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Share to Chronic Obstructive Pulmonary Disease (COPD) Research
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PMID: 34017996
DOI: 10.1042/bsr20210308

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