Article
Bioinformatics analysis of PLA2G7 as an immune-related biomarker in COPD by promoting expansion and suppressive functions of MDSCs.
International immunopharmacology - 1 Jul 2023
Zhao Xiaoyu, Yue Yuanyi, Wang Xueqing, Zhang Qiang
Abstract excerpt
BACKGROUND: Immune mechanism is involved in the pathogenesis of chronic obstructive pulmonary disease (COPD). However, the exact immune pathogenesis still remains unclear. This study aimed to identify the immune-related biomarkers in COPD through bioinformatics analysis and its potential molecular mechanism. METHODS: GSE76925 was downloaded from Gene Expression Omnibus (GEO) database. Differentially expressed...
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