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Identification of biomarkers and pathogenesis in severe asthma by coexpression network analysis

18 Feb 2021

Abstract excerpt

BACKGROUND: Severe asthma is a heterogeneous inflammatory disease. The increase in precise immunotherapy for severe asthmatics requires a greater understanding of molecular mechanisms and biomarkers. In this study, we aimed to identify the underlying mechanisms and hub genes that determine asthma severity. METHODS: Differentially expressed genes (DEGs) were identified based on bronchial epithelial brushings from...

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PMID: 33602227
DOI: 10.1186/s12920-021-00892-4

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