Article
Contamination Assessment for Cancer Next-Generation Sequencing.
Archives of pathology & laboratory medicine - 2 Jan 2022
Li Yvonne Y, Schmidt Ryan J, Manning Danielle K, Jia Yonghui, Dong Fei
Abstract excerpt
CONTEXT.—: The presence of allogeneic contamination impacts clinical reporting in cancer next-generation sequencing specimens. Although consensus guidelines recommend the identification of contaminating DNA as a part of quality control, implementation of contamination assessment methods in clinical molecular diagnostic laboratories has not been reported in the literature. OBJECTIVE.—: To develop and implement a...
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