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Article

The mutagenic impact of melphalan in multiple myeloma.

Leukemia - 1 Aug 2021

Maura Francesco, Weinhold Niels, Diamond Benjamin, Kazandjian Dickran, Rasche Leo, Morgan Gareth, Landgren Ola

Abstract excerpt

The introduction of whole genome and exome sequencing partnered with advanced bioinformatic pipelines has allowed the comprehensive characterization of mutational processes (i.e., mutational signatures) in individual cancer patients. Studies focusing on multiple myeloma have defined several mutational processes, including a recently identified mutational signature (called "SBS-MM1") directly caused by exposure to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34012133
DOI: 10.1038/s41375-021-01293-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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