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Liver development is restored by blastocyst complementation of HHEX knockout in mice and pigs

19 May 2021

Abstract excerpt

BACKGROUND: There are over 17,000 patients in the US waiting to receive liver transplants, and these numbers are increasing dramatically. Significant effort is being made to obtain functional hepatocytes and liver tissue that can for therapeutic use in patients. Blastocyst complementation is a challenging, innovative technology that could fundamentally change the future of organ transplantation. It requires the...

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PMID: 34011403
DOI: 10.1186/s13287-021-02348-z

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