Article

<i>In vivo</i> generation of heart and vascular system by blastocyst complementation

2022-10-04

Abstract excerpt

<h4>SUMMARY</h4> The generation of organs from stem cells by blastocyst complementation is a promising approach to cover the clinical need for transplants. In order to generate rejection-free organs, complementation of both parenchymal and vascular cells must be achieved, as endothelial cells play a key role in graft rejection. Here we used a lineage-specific cell ablation system to produce mouse embryos unable t...

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Literature Corpus work: 3bad3af3-2c58-5b50-8410-1bbaea8f14e2
DOI: 10.1101/2022.10.04.510637

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