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Liver development and regeneration: From laboratory study to clinical therapy

1 Feb 2007

Abstract excerpt

The liver has an unusual capacity to regenerate after a loss of mass and function caused by surgical resection or toxic liver injury. Over the last 10 years there have been major advances in our understanding of the molecular and cellular mechanisms underlying liver development and regeneration. The numerous factors crucial to these phenomena have been identified mainly by using knockout mice. Forward-genetics...

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PMID: 17335437
DOI: 10.1111/j.1440-169x.2007.00910.x

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