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Article

High-resolution profiling of pathways of escape for SARS-CoV-2 spike-binding antibodies.

Cell - 27 May 2021

Garrett Meghan E, Galloway Jared, Chu Helen Y, Itell Hannah L, Stoddard Caitlin I, Wolf Caitlin R, Logue Jennifer K, McDonald Dylan, Weight Haidyn, Matsen Frederick A, Overbaugh Julie

Abstract excerpt

Defining long-term protective immunity to SARS-CoV-2 is one of the most pressing questions of our time and will require a detailed understanding of potential ways this virus can evolve to escape immune protection. Immune protection will most likely be mediated by antibodies that bind to the viral entry protein, spike (S). Here, we used Phage-DMS, an approach that comprehensively interrogates the effect of all...

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Share to Antibodies, Neutralizing
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34010620
DOI: 10.1016/j.cell.2021.04.045
PMCID: PMC8096189

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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