Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants.

doi:10.7554/eLife.61312

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Article

Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants.

eLife - 28 Oct 2020

Weisblum Yiska, Schmidt Fabian, Zhang Fengwen, DaSilva Justin, Poston Daniel, Lorenzi Julio Cc, Muecksch Frauke, Rutkowska Magdalena, Hoffmann Hans-Heinrich, Michailidis Eleftherios, Gaebler Christian, Agudelo Marianna, Cho Alice, Wang Zijun, Gazumyan Anna, Cipolla Melissa, Luchsinger Larry, Hillyer Christopher D, Caskey Marina, Robbiani Davide F, Rice Charles M, Nussenzweig Michel C, Hatziioannou Theodora, Bieniasz Paul D

Abstract excerpt

Neutralizing antibodies elicited by prior infection or vaccination are likely to be key for future protection of individuals and populations against SARS-CoV-2. Moreover, passively administered antibodies are among the most promising therapeutic and prophylactic anti-SARS-CoV-2 agents. However, the degree to which SARS-CoV-2 will adapt to evade neutralizing antibodies is unclear. Using a recombinant chimeric...

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Identifiers

PMID: 33112236
DOI: 10.7554/eLife.61312
PMCID: PMC7723407

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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