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Article

PALB2 mutations and prostate cancer risk and survival.

British journal of cancer - 1 Aug 2021

Wokołorczyk Dominika, Kluźniak Wojciech, Stempa Klaudia, Rusak Bogna, Huzarski Tomasz, Gronwald Jacek, Gliniewicz Katarzyna, Kashyap Aniruddh, Morawska Sylwia, Dębniak Tadeusz, Jakubowska Anna, Szwiec Marek, Domagała Paweł, Lubiński Jan, Narod Steven A, Akbari Mohammad R, Cybulski Cezary

Abstract excerpt

BACKGROUND: The objective of this study was to establish the contribution of PALB2 mutations to prostate cancer risk and to estimate survival among PALB2 carriers. METHODS: We genotyped 5472 unselected men with prostate cancer and 8016 controls for two Polish founder variants of PALB2 (c.509_510delGA and c.172_175delTTGT). In patients with prostate cancer, the survival of carriers of a PALB2 mutation was compared...

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Identifiers

PMID: 34006922
DOI: 10.1038/s41416-021-01410-0
PMCID: PMC8368211

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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