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Article

Altered expression of the CB1 cannabinoid receptor in the triple transgenic mouse model of Alzheimer's disease.

Journal of Alzheimer's disease : JAD - 1 Jan 2014

Bedse Gaurav, Romano Adele, Cianci Silvia, Lavecchia Angelo M, Lorenzo Pace, Elphick Maurice R, Laferla Frank M, Vendemiale Gianluigi, Grillo Caterina, Altieri Fabio, Cassano Tommaso, Gaetani Silvana

Abstract excerpt

The endocannabinoid system has gained much attention as a new potential pharmacotherapeutic target in various neurodegenerative diseases, including Alzheimer's disease (AD). However, the association between CB1 alterations and the development of AD neuropathology is unclear and often contradictory. In this study, brain CB1 mRNA and CB1 protein levels were analyzed in 3 × Tg-AD mice and compared to wild-type...

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PMID: 24496074
DOI: 10.3233/JAD-131910

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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