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From Synaptic Plasticity to Neurotoxicity: Endocannabinoid Influence on Addiction and Neurodegeneration

2025-10-24

Abstract excerpt

The endocannabinoid system (eCBS) is a versatile neuromodulatory network that orchestrates synaptic plasticity, reward processing, and neuronal homeostasis. Increasing evidence implicates eCBS dysregulation in both addiction and neurodegenerative (ND) disorders, suggesting overlapping molecular and cellular mechanisms that underlie these conditions. This review synthesizes current advances in understanding how eCB...

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Literature Corpus work
ad1c53aa-bb0a-556d-ad57-f99918175bed
DOI
10.20944/preprints202510.1917.v1
Open publication

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