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Article

Mutations in GBA and LRRK2 Are Not Associated with Increased Inflammatory Markers.

Journal of Parkinson's disease - 1 Jan 2021

Thaler Avner, Omer Nurit, Giladi Nir, Gurevich Tanya, Bar-Shira Anat, Gana-Weisz Mali, Goldstein Orly, Kestenbaum Meir, Shirvan Julia C, Cedarbaum Jesse M, Orr-Urtreger Avi, Regev Keren, Shenhar-Tsarfaty Shani, Mirelman Anat

Abstract excerpt

BACKGROUND: Inflammation is an integral part of neurodegeneration including in Parkinson's disease (PD). Ashkenazi Jews have high rates of genetic PD with divergent phenotypes among GBA-PD and LRRK2-PD. The role of inflammation in the prodromal phase of PD and the association with disease phenotype has yet to be elucidated. OBJECTIVE: To assess central and peripheral cytokines among PD patients with mutations in...

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Source

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Identifiers

PMID: 33998549
DOI: 10.3233/JPD-212624
PMCID: PMC8461659

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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