Article
Cytokines and Gaucher Biomarkers in Glucocerebrosidase Carriers with and Without Parkinson Disease.
Movement disorders : official journal of the Movement Disorder Society - 1 Jun 2021
Galper Jasmin, Balwani Manisha, Fahn Stanley, Waters Cheryl, Krohn Lynne, Gan-Or Ziv, Dzamko Nicolas, Alcalay Roy N
Abstract excerpt
BACKGROUND: Homozygous and compound heterozygous variants in glucocerebrosidase (GBA) can cause Gaucher disease (GD), whereas heterozygous variants increase the risk of developing Parkinson's disease (PD). GD patients display altered peripheral immune proteins. However, it is unknown if these are altered in GBA carriers with PD. OBJECTIVES: To determine whether plasma cytokines and immune biomarkers associated...
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