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Article

NP-59 Adrenal Scintigraphy as an Imaging Biomarker to Predict KCNJ5 Mutation in Primary Aldosteronism Patients.

Frontiers in endocrinology - 1 Jan 2021

Lu Ching-Chu, Yen Ruoh-Fang, Peng Kang-Yung, Huang Jei-Yie, Wu Kwan-Dun, Chueh Jeff S, Lin Wan-Yu

Abstract excerpt

Purpose: Somatic KCNJ5 mutation occurs in half of unilateral primary aldosteronism (PA) and is associated with more severe phenotype. Mutation status can only be identified by tissue sample from adrenalectomy. NP-59 adrenal scintigraphy is a noninvasive functional study for disease activity assessment. This study aimed to evaluate the predictive value of NP-59 adrenal scintigraphy in somatic KCNJ5 mutation among...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Adrenocortical Adenoma

Share to G Protein-Coupled Inwardly-Rectifying Potassium Channels

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Share to Radionuclide Imaging

Share to Tomography, Emission-Computed, Single-Photon

Source

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Identifiers

PMID: 33995277
DOI: 10.3389/fendo.2021.644927
PMCID: PMC8113947

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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