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Article

Aldosterone-producing adenoma-harbouring KCNJ5 mutations is associated with lower prevalence of metabolic disorders and abdominal obesity.

Journal of hypertension - 1 Dec 2021

Chen Kuan-Ming, Chang Yu-Ling, Wu Tung-Hsin, Lee Bo-Ching, Chen Po-Ting, Liu Kao-Lang, Hong Jia-Sheng, Chang Chin-Chen, Wu Vin-Cent, Lin Yen-Hung

Abstract excerpt

OBJECTIVE: Aldosterone overproduction and lipid metabolic disturbances between idiopathic hyperaldosteronism (IHA) and unilateral aldosterone-producing adenoma (APA) have been inconsistently linked in patients with primary aldosteronism. Moreover, KCNJ5 mutations are prevalent among APAs and enhance aldosterone synthesis in adrenal cortex. We aimed to investigate the prevalence of metabolic syndrome (MetS) in...

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Share to Adrenal Cortex Neoplasms
Share to Adrenocortical Adenoma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to G Protein-Coupled Inwardly-Rectifying Potassium Channels

Share to Hyperaldosteronism

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Identifiers

PMID: 34313632
DOI: 10.1097/HJH.0000000000002948

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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