Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Associations of Genetically Predicted Plasma Alanine with Coronary Artery Disease and its Risk Factors: A Mendelian Randomization Study.

The American journal of clinical nutrition - 1 Nov 2023

Huang Xin, Zhao Jie V

Abstract excerpt

BACKGROUND: Alanine is an amino acid commonly used as a nutritional supplement and plays a key role in the glucose-alanine cycle. Plasma alanine has been associated in observational studies with a higher risk of coronary artery disease (CAD) and unhealthier lipid profiles. However, evidence from large randomized controlled trials is lacking. OBJECTIVES: Using Mendelian randomization (MR), we assessed the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alanine
Share to Apolipoproteins
Share to Cholesterol

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cholesterol, HDL

Share to Cholesterol, LDL

Share to Coronary Artery Disease

Share to Diabetes Mellitus

Share to Triglycerides

Source

Identifiers

PMID: 37640107
DOI: 10.1016/j.ajcnut.2023.08.011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Associations of Genetically Predicted Plasma Alanine with Coronary Artery Disease and its Risk Factors: A Mendelian Randomization Study.PMID 37640107Read ↗

Unravelling the role of alanine in mental disorders: a Mendelian randomisation study.Semantic proximity Read ↗

Mendelian randomization estimates of alanine aminotransferase with cardiovascular disease: Guangzhou Biobank Cohort study.Semantic proximity Read ↗

Association of Lipid Fractions With Risks for Coronary Artery Disease and Diabetes.Semantic proximity Read ↗

The association of alanine aminotransferase and diabetic microvascular complications: A Mendelian randomization studySemantic proximity Read ↗

Causal relationships between genetically predicted circulating levels of amino acids and non-alcoholic fatty liver disease risk: a Mendelian randomisation studySemantic proximity Read ↗

Causal relationships of circulating amino acids with cardiovascular disease: a trans-ancestry Mendelian randomization analysis.Semantic proximity Read ↗

A Mendelian Randomization Study of Metabolite Profiles, Fasting Glucose, and Type 2 Diabetes.Semantic proximity Read ↗

Novel genetic insights into the roles of amino acids in metabolic dysfunction-associated steatotic liver diseaseSemantic proximity Read ↗

Assessment of Causal Direction Between Gut Microbiota–Dependent Metabolites and Cardiometabolic Health: A Bidirectional Mendelian Randomization AnalysisSemantic proximity Read ↗

Genetic Causal Relationship Between Alanine Aminotransferase Levels and Risk of Gestational Diabetes Mellitus: Mendelian Randomization Analysis Based on Two Samples.Semantic proximity Read ↗

Genetically Higher Level of Mannose Has No Impact on Cardiometabolic Risk Factors: Insight from Mendelian Randomization.Semantic proximity Read ↗

Effect of Genetic and Dietary Perturbation of Glycine Metabolism on Atherosclerosis in Humans and MiceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.