Article
Diabetic cataract in the Nile grass rat: A longitudinal phenotypic study of pathology formation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Jun 2021
Ranaei Pirmardan Ehsan, Barakat Aliaa, Zhang Yuanlin, Naseri Marzieh, Hafezi-Moghadam Ali
Abstract excerpt
Diabetes is a major risk factor for cataract, the leading cause of blindness worldwide. There is an unmet need for a realistic model of diabetic cataract for mechanistic and longitudinal studies, as existing models do not reflect key aspects of the complex human disease. Here, we introduce and characterize diabetic cataract in the Nile grass rat (NGR, Arvicanthis niloticus), an established model of metabolic...
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