Article

Metabolomic Changes in the Rat Eye Lens During the Cataract Onset

2026-05-19

Abstract excerpt

This study aimed to characterize metabolomic changes in the eye lens of senescence-accelerated OXYS rats in comparison with control Wistar rats, and to identify biochemical shifts associated with genotype, age, and cataract progression. Cataract severity was clinically graded. Rats' lenses were analyzed using quantitative 1H NMR spectroscopy at 3.6 and approximately 4.5 months of age. A total of 43 metabolites wer...

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Literature Corpus work: 15f3aa19-3c78-5c0f-9182-02a225ffd474
DOI: 10.20944/preprints202605.1154.v1

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