Article
Gene profiles and mutations in the development of cataracts in the ICR rat model of hereditary cataracts.
Scientific reports - 24 Oct 2023
Takashima Masaru, Taniguchi Kei, Nagaya Masaya, Yamamura Shunki, Takamura Yoshihiro, Inatani Masaru, Oki Masaya
Abstract excerpt
Cataracts are opacifications of the lens that cause loss of visual acuity and ultimately of eyesight. Age-related cataract develops in most elderly people, but the mechanisms of cataract onset are incompletely understood. The Ihara Cataract Rat (ICR) is an animal model of hereditary cataracts showing cortical opacity that commonly develops prematurely. We identified putative mechanisms of cataract onset in the...
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