Article
Importance of clonal hematopoiesis in heart failure.
Trends in cardiovascular medicine - 1 May 2022
Chavkin Nicholas W, Min Kyung-Duk, Walsh Kenneth
Abstract excerpt
Heart failure is prevalent in the elderly population. Inflammatory processes can contribute to the progression of heart failure by altering the balance of tissue healing and pathological remodeling during the injury response. New findings show that aging can alter immune cell phenotypes through the process of clonal hematopoiesis. This condition results from acquired somatic DNA mutations in specific driver genes...
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