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Article

MEF2C silencing downregulates NF2 and E-cadherin and enhances Erastin-induced ferroptosis in meningioma

8 May 2021

Abstract excerpt

BACKGROUND: Ferroptosis, a programmed cell death characterized by lipid peroxidation, is implicated in various diseases including cancer. Although cell density-dependent E-cadherin and Merlin/Neurofibromin (NF2) loss can modulate ferroptosis, the role of ferroptosis and its potential link to NF2 status and E-cadherin expression in meningioma remain unknown. METHODS: Relationship between ferroptosis modulators...

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PMID: 33984142
DOI: 10.1093/neuonc/noab114

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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